Explore the guide and start building a roadmap to expand access to CGP: https://pcc-cgpimplementationguide.avalerehealth.com/

Comprehensive Genomic Profiling (CGP) identifies the full set of biomarkers needed to guide clinical decision-making. It enables access to approved targeted therapies and clinical trials and is becoming essential in the management of many cancers.

To expand global access to comprehensive genomic testing, the PCC has developed The Pathway to Precision Cancer Care: A Strategic and Operational Guide to Enhance Patient Access to CGP – a practical, system-level resource for health ministries, providers, cancer program leaders, institutions, and consortia seeking to embed CGP into routine cancer care.

Limited CGP capability has significant implications for patients, clinicians, and health systems. Without coordinated action:

• Patient care suffers, with missed opportunities for accurate diagnosis, targeted therapies, clinical trials, and improved outcomes
• Costs rise due to inefficient use of testing resources
• Results may be delayed or misinterpreted because of the complexity of genomic data and shortages in specialized expertise
• Patients and families receive insufficient information, limiting confidence and shared decision-making
• Potential economic benefits are lost as investment in CGP offers the prospect of delivering substantial economic value that extends beyond healthcare alone

By tackling these barriers, health systems can move closer to equitable, sustainable precision oncology for all patients.

Designed for diverse health systems, the guide offers adaptable, actionable steps, practical tools, and real-world examples to help organizations initiate, scale, and strengthen CGP programs. It addresses the critical challenges that currently limit access.

The guide supports implementation across countries and tumor types through three core pillars:

1. System setup
2. Quality assurance
3. Workforce capability

Each pillar addresses key adoption challenges and includes clear milestones, planning tools, and practical examples to help teams assess their current state and build a tailored roadmap to launch, expand, and sustain CGP services.

PCC-257 | Date: February 2026